PAX2 expression in low malignant potential ovarian tumors and low-grade ovarian serous carcinomas

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Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.

Papillary serous low malignant potential (LMP) tumors are characterized by malignant features and metastatic potential yet display a benign clinical course. The role of LMP tumors in the development of invasive epithelial cancer of the ovary is not clearly defined. The aim of this study is to determine the relationships among LMP tumors and invasive ovarian cancers and identify genes contributi...

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The article by Trimble and Trimble nicely summarizes the state of knowledge on ovarian tumors of low malignant potential (LMP) and underscores the fact that gaps in that knowledge have led to confusion and controversy regarding several issues related to these interesting neoplasms. Many of these controversies can be characterized as debates between the "lumpers" and the "splitters.' The Johns H...

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Executive Summary Ovarian tumors of low malignant potential can be a challenge in daily underwriting, as even clinicians are not in full agreement about the correct approach. This article sheds light on this tumor and highlights some of the key favorable factors when underwriting this condition. INTRODUCTION Ovarian tumors of low malignant potential, also known as borderline tumors of the ovary...

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The role of serous tumors of low malignant potential (LMP) in the development of invasive epithelial cancer of the ovary is debatable. This review summarizes the current clinical, genetic, and genomic evidence for the existence of a continuum comprising both LMP serous tumors and low-grade serous ovarian carcinomas.

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ژورنال

عنوان ژورنال: Modern Pathology

سال: 2009

ISSN: 0893-3952,1530-0285

DOI: 10.1038/modpathol.2009.92